Citalopram is a commonly prescribed antidepressant used to treat depression and various anxiety-related conditions. It belongs to the class of medications known as selective serotonin reuptake inhibitors (SSRIs), which work by increasing serotonin levels in the brain. Serotonin plays a vital role in mood regulation, sleep, and overall emotional well-being.

Citalopram is known by the brand name Celexa and is often considered a first-line treatment for individuals experiencing moderate to severe symptoms of depression or anxiety. At My Psychiatrist, we use medications like Citalopram as part of a comprehensive care plan that may also include talk therapy, lifestyle modifications, or other advanced treatments like TMS.

What Citalopram Is Used For

Citalopram is primarily prescribed to treat major depressive disorder (MDD), but it’s also frequently used off-label for a number of related mental health conditions. These include:

• Generalized anxiety disorder (GAD)
• Social anxiety disorder
• Panic disorder
• Obsessive-compulsive disorder (OCD)
• Post-traumatic stress disorder (PTSD)
• Premenstrual dysphoric disorder (PMDD)

It is often chosen for its effectiveness, relatively low risk of side effects, and safety profile. It can be used for both short-term symptom relief and long-term maintenance, depending on the needs of the patient.

How Citalopram Works

Citalopram works by blocking the reuptake of serotonin in the brain, making more serotonin available to transmit messages between nerve cells. This increase helps stabilize mood and alleviate symptoms of depression and anxiety.

Citalopram is usually taken once daily, with or without food. The dose varies depending on the individual and their specific symptoms, and your provider will work closely with you to find the right balance. It may take several weeks to feel the full benefit, although some individuals notice subtle improvements earlier.

Starting Citalopram: What to Expect

Like most antidepressants, Citalopram doesn’t work instantly. Most people begin to notice gradual improvements in mood, energy, and concentration within 2–4 weeks, although full effects often take 6–8 weeks.

It’s not uncommon to experience some side effects when starting Citalopram, especially in the first few days. These may include:

• Nausea
• Dry mouth
• Increased sweating
• Tiredness or drowsiness
• Difficulty sleeping
• Mild anxiety or restlessness

These side effects typically lessen as your body adjusts. Staying in touch with your provider during this time is essential, especially if you experience anything unusual or distressing.

Symptoms Citalopram Can Help Alleviate

Citalopram can be effective in treating a range of mental health symptoms, including:

• Persistent sadness or low mood
• Loss of interest in daily activities
• Excessive worry or fear
• Difficulty sleeping due to racing thoughts
• Irritability or agitation
• Fatigue and low energy
• Trouble focusing or making decisions

Because every person’s experience with depression or anxiety is different, treatment with Citalopram is always tailored to individual needs.

Important Considerations and Safety

Citalopram is generally well-tolerated, but it may not be suitable for everyone. People with certain heart conditions or those taking medications that affect heart rhythm may need special monitoring. High doses of Citalopram have been associated with an increased risk of QT prolongation, a type of irregular heartbeat.

It’s also important to avoid combining Citalopram with other medications that affect serotonin levels, such as other SSRIs, MAOIs, or certain migraine treatments, as this can increase the risk of serotonin syndrome.

Citalopram should never be stopped abruptly. Tapering off under a provider’s guidance helps prevent withdrawal symptoms such as dizziness, irritability, and flu-like symptoms.

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FAQs About Citalopram

Is Citalopram addictive?
Citalopram is not addictive and doesn’t produce a “high,” but stopping it suddenly can lead to withdrawal symptoms. Always consult your provider before discontinuing.

Can Citalopram help with anxiety?
Yes, Citalopram is often used to treat various anxiety disorders and is effective in reducing chronic worry, panic attacks, and social anxiety symptoms.

How long will I need to take it?
Some people take Citalopram for several months, while others may use it for years. Your provider will regularly evaluate your progress and determine the appropriate duration.

Will I gain weight on Citalopram?
Some individuals report weight changes, but many do not. Maintaining a healthy diet and staying active can help minimize weight-related effects.

Does Citalopram affect sleep?
It can cause either drowsiness or insomnia, especially in the beginning. These effects usually improve over time as your body adjusts.

Can I drink alcohol while taking Citalopram?
It’s best to limit or avoid alcohol, as it can worsen side effects like drowsiness and interfere with the effectiveness of the medication.

What if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—don’t double up. Always follow your provider’s instructions.

Citalopram Support at My Psychiatrist

If you’re considering Citalopram or currently using it and have questions, our team at My Psychiatrist is here to support you. With six outpatient locations across South and Central Florida and telehealth options available, we offer convenient, compassionate care for patients facing depression, anxiety, and other mental health challenges.

Our providers work with you to understand your goals and symptoms and help guide you toward the most effective and comfortable treatment plan. If you’d like to learn more about how Citalopram could fit into your care, reach out today to schedule an appointment.

Sources:

National Library of Medicine – Citalopram Overview
FDA Celexa (Citalopram) Medication Guide
NHS – Citalopram: Uses, Side Effects, and Safety
Mayo Clinic – Citalopram (Oral Route) Description and Usage
PsychCentral – In-Depth Guide to Celexa